You might want to add "C:\qt-win-opensource-src-4.3.3\bin" to PATH so that you can run qmake conveniently. The next step is to create a cross-platform qmake project file (.pro) from which qmake is able to generate a Visual Studio project file (.vcproj) for you. (Furthermore, qmake is able to generate makefiles for all supported platforms/compilers.)

Go grab Hello World and save it to an empty directory, let's say C:\HelloWorld:
C:\HelloWorld> qmake -project
C:\HelloWorld> qmake -tp vc
First command creates an initial cross-platform .pro file from detected source files in that directory. Second command creates a Visual Studio project file based on the .pro file. Open the .vcproj in Visual Studio and build. Voilá!