Qmake

[jacek]

How do i config it to be able to run commands like: "make debug" and "make release"

You can also add:

CONFIG += debug_and_release

to your .pro file and then use make -f Makefile.Release and make -f Makefile.Debug.

[fullmetalcoder]

You can also add:to your .pro file and then use make -f Makefile.Release and make -f Makefile.Debug.

Another (simpler) syntax that can be used along the debug_and_release option is :
$ make release
or :
$ make debug