You mean the Y axis?
No, I meant the X axis, visually.
Which means inverting the y component.

Did you mean inverted (multiplied with -1)?
Yes, exactly. It should be OK if you apply a scale of (1, -1).

What about performance issue with all this scaling? Schematics can have from about 10 to 100 symbols and a lot of nets (lines) that connect the symbols, PCB are usually even bigger. Can this be a problem?
I am not sure about that, because it depends on the complexity of the items.
It actually all comes down to repainting the view.
There are a few recent posts regarding graphics view performance. Maybe those can be of some help.

Regards